Obecność covid potwierdzona w przewodzie pokarmowym wiele miesięcy po infekcji. Śmiertelnie niebezpieczny wielonarządowy syndrom zapalny u dzieci jest związany ze zwiększonym przenikaniem covid z przewodu pokarmowego do krwioobiegu. Czy długi covid to po prostu ciągła obecność pozostałości wirusa w przewodzie pokarmowym i gdyby je w jakiś sposób usunąć, choroba by zniknęła? Czy ''uszczelnienie jelit'' wyleczy z długiego covida?
''In adults, there is increased recognition that the gut serves as a nidus for SARS-CoV-2 (12) and that in severe COVID-19, dysbiosis and disruption of the GI barrier drive inflammatory activation (13, 14).''
''We showed that in children with MIS-C, a prolonged presence of SARS-CoV-2 in the GI tract led to the release of zonulin, a biomarker of intestinal permeability, with subsequent trafficking of SARS-CoV-2 antigens into the bloodstream, leading to hyperinflammation. The patient with MIS-C treated with larazotide had a coinciding decrease in plasma SARS-CoV-2 spike antigen levels and inflammatory markers and a resultant clinical improvement above that achieved with currently available treatments.''
https://www.jci.org/articles/view/149633
The researchers found that these improved antibodies are produced by immune cells that have kept evolving, apparently due to a continued exposure to the remnants of the virus hidden in the gut tissue. [które zostały stwierdzone trzy miesiące po infekcji]
''We were surprised to see the memory B cells had kept evolving during this time,” Nussenzweig says. “That often happens in chronic infections, like HIV or herpes, where the virus lingers in the body. But we weren’t expecting to see it with SARS-CoV-2, which is thought to leave the body after infection has resolved.”
https://www.rockefeller.edu/news/30005-s...protection
''In adults, there is increased recognition that the gut serves as a nidus for SARS-CoV-2 (12) and that in severe COVID-19, dysbiosis and disruption of the GI barrier drive inflammatory activation (13, 14).''
''We showed that in children with MIS-C, a prolonged presence of SARS-CoV-2 in the GI tract led to the release of zonulin, a biomarker of intestinal permeability, with subsequent trafficking of SARS-CoV-2 antigens into the bloodstream, leading to hyperinflammation. The patient with MIS-C treated with larazotide had a coinciding decrease in plasma SARS-CoV-2 spike antigen levels and inflammatory markers and a resultant clinical improvement above that achieved with currently available treatments.''
https://www.jci.org/articles/view/149633
The researchers found that these improved antibodies are produced by immune cells that have kept evolving, apparently due to a continued exposure to the remnants of the virus hidden in the gut tissue. [które zostały stwierdzone trzy miesiące po infekcji]
''We were surprised to see the memory B cells had kept evolving during this time,” Nussenzweig says. “That often happens in chronic infections, like HIV or herpes, where the virus lingers in the body. But we weren’t expecting to see it with SARS-CoV-2, which is thought to leave the body after infection has resolved.”
https://www.rockefeller.edu/news/30005-s...protection